9 Best Left-Handed Mouse with Side Buttons (November 2026)
The best left handed mice with side buttons include the SHARE SUNSHINE Wireless Mouse Ergonomic Vertical Left-Handed Mouse for adjustable DPI on a budget, the Logitech Left Handed Lift Vertical Ergonomic Wireless for quiet everyday work, and the エレコム for a left-hand trackball.
On this page (5 sections)
The best left handed mouse with side buttons is the Logitech Lift for most daily work, while SHARE SUNSHINE offers the strongest mix of vertical shape, six buttons and adjustable DPI. Razer Naga is the specialist choice when programmable thumb controls matter more than a simple office layout.
This list focuses on left-hand mice with forward and backward controls, programmable buttons or both. We compared the stated button layouts, connection types, hand guidance, DPI settings and power options.
That comparison matters because side buttons solve different problems for different people. A browsing button saves a trip to the address bar, while a programmable button can hold a shortcut you use many times a day.
Hand fit also changes the value of the same button layout. A vertical mouse that suits a small hand may feel cramped for a larger one, and a trackball places control under the thumb instead of moving the whole body.
Connection choice affects daily setup as well. Some models use a USB receiver, some use Bluetooth, and some are wired, so the best pick depends on whether you move between devices or stay at one desk.
If you want a broader starting point, our guide to the best left handed mouse compares other left-hand designs. For keyboard pairing at the same workstation, see our guide to the best keyboard for computer.
Read the picks below by the task you do most. Office browsing needs simple controls and quiet clicks, while gaming or editing may justify the extra setup that programmable buttons require.
We kept the focus on stated specs rather than promises about comfort. You should still measure your hand and check your operating system before you order.
Our picks at a glance
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1
Best for adjustable DPI on a budgetSHARE SUNSHINE Wireless Mouse Ergonomic Vertical Left-Handed Mouse
9.7/10 our score
See it on Amazon -
2
Best for quiet everyday workLogitech Left Handed Lift Vertical Ergonomic Wireless
9.7/10 our score
See it on Amazon -
3
- 4
Check itPerixx Perimice-513L Wired Vertical Ergonomic Mouse
Best for a wired office setup - 5
Best for small to medium handsCheck it - 6
Check itRazer RZ01-01050100-R3M1 Naga Left-Handed
Best for MMO button control - 7
Check itMEETION Left-Handed Wireless Ergonomic Vertical Mouse
Best for rechargeable multi-device use - 8
Best for a switchable office mouseCheck it - 9
Best for basic wireless ergonomicsCheck it
Which left handed mouse with side buttons is best for work?
The Logitech Lift is the best work pick for small to medium left hands, while Perixx is the better fit for a wired desk. Both provide side controls, but they take different approaches to power and connection.
SHARE SUNSHINE Wireless Mouse Ergonomic Vertical Left-Handed Mouse: Best for adjustable DPI on a budget
- Left-handed vertical design
- 6 buttons
- 800/1200/1600 DPI
- Forward and backward side buttons
This wireless vertical mouse combines left-hand shaping with forward and backward buttons for browsing. Three DPI settings let you adjust cursor speed for office work, general use or casual gaming.
Pros
- Left-handed vertical shape
- Three DPI settings
- Six-button layout
Cons
- Batteries are not included
- Forward and backward buttons are not recognized on Mac OS X
SHARE SUNSHINE is a practical choice when you want a left-handed vertical mouse with forward and backward buttons and three sensitivity levels. The 800, 1200 and 1600 DPI options let you slow the pointer for precise work or increase movement speed across a larger screen.
Its six-button layout includes left and right click, a scroll wheel, DPI control and the two side buttons. The wireless connection uses a USB receiver, and the stated compatible systems include Windows, Mac OS and Linux.
The included receiver is stored in the mouse. Batteries are not included, so plan for that before setting up the mouse.
One Mac OS limitation matters here: the forward and backward buttons are not recognized on Mac OS X. Choose SHARE SUNSHINE when adjustable DPI and a left-hand vertical grip matter more than Mac side-button support.
For everyday office work, the middle DPI setting is a sensible starting point. You can raise it when moving across a large monitor and lower it for small targets.
The vertical shape suits users who prefer an upright handshake grip. Give it a few days to adjust if you are coming from a flat mouse, and check that your fingers reach the side buttons without stretching.
Logitech Left Handed Lift Vertical Ergonomic Wireless: Best for quiet everyday work
- 57-degree vertical shape
- Customizable buttons
- Whisper-quiet clicks
- Bluetooth and Logi Bolt connectivity
The Logitech Lift is a strong daily-work choice for small to medium left hands. Its 57-degree shape, quiet clicks, SmartWheel and customizable buttons cover common office tasks without a cable.
Pros
- Quiet clicks
- Customizable buttons
- Bluetooth and Logi Bolt options
Cons
- Designed for small to medium hands
- Uses a single AA battery
Logitech Lift suits small to medium left hands and uses a 57-degree vertical shape. Its softly textured grip, thumb rest, SmartWheel and whisper-quiet clicks target long work sessions where noise and hand position both matter.
The mouse has 6 buttons, with customizable controls through Logitech software. It connects through Bluetooth Low Energy or the included Logi Bolt USB receiver, so you can choose the connection that fits your computer.
A single AA battery is rated for up to 24 months. The package includes the mouse, one AA battery, the Logi Bolt receiver and a quick-start guide.
Choose Lift if you want a polished office mouse with side controls and quiet clicks. For a more detailed ergonomic comparison, see the best left handed ergonomic mouse guide.
If you switch between a laptop and a desktop, the dual connection options can reduce setup friction. Bluetooth suits a laptop without tying up a USB port, while the receiver may feel more direct on a fixed PC.
Keep the grip clean with a dry cloth and avoid pressing hard on the thumb rest. A light touch will help the textured surface last and keep clicks consistent.
エレコム: Best for a left-hand trackball
- Thumb-controlled trackball
- 6 programmable buttons
- 750/1500 DPI switch
- 2.4 GHz wireless connection
The ELECOM EX-G puts cursor control under the left thumb instead of relying on a sliding mouse body. Six buttons can be assigned through ELECOM Mouse Assistant software, while the DPI button switches between 750 and 1500.
Pros
- Programmable six-button layout
- Thumb-controlled cursor movement
- Wireless design
Cons
- Trackball control takes adjustment
- Uses a larger body than a standard mouse
ELECOM EX-G is the best fit if you want programmable buttons with trackball control. Its left-hand thumb-operated trackball reduces the need to slide the whole mouse, while the 6-button layout supports assignments through ELECOM Mouse Assistant software.
The DPI button switches between 750 and 1500. Its wireless connection uses 2.4 GHz USB, and the mouse works with personal computers, Macs and tablets.
The mouse uses 1 AA battery, which is included. Its stated dimensions are 3.7 x 4.9 x 1.9 in, and its weight is 4.5 oz without the battery.
Trackball control feels different from a standard optical mouse, so expect an adjustment period. If that control style appeals to you, compare it with our guide to the best left handed trackball mouse.
The lower DPI setting helps with careful cursor placement, while the higher setting suits faster movement across a screen. Start with the lower setting while you learn the ball response, then switch as your thumb control improves.
Keeping the ball and its housing clean helps maintain smooth movement. A periodic wipe with a soft dry cloth is enough, and you should avoid using the mouse on a surface that sheds lint into the trackball area.
Perixx Perimice-513L Wired Vertical Ergonomic Mouse: Best for a wired office setup
- Left-handed vertical design
- 6 buttons
- 1000/1600 DPI switch
- 1.8 m USB cable
The Perixx Perimice-513L gives left-handed users a wired vertical shape, two browsing side buttons and a two-level DPI switch. Its 1.8 m cable suits a fixed desk where charging and wireless receivers are unwanted.
Pros
- No battery required
- Rubber-coated surface
- Side buttons for browsing
Cons
- Cable limits desk movement
- Only two DPI levels
Perixx Perimice-513L is the wired choice for a fixed workstation. Its left-handed vertical shape, rubber-coated surface, 6 buttons and 1.8 m USB cable keep the setup simple.
The two side buttons are designed for internet browsing, and the DPI switch offers 1000 or 1600. Because it is corded, you do not need batteries or a wireless receiver.
Perixx describes the shape as suitable for different hand sizes. The mouse is compatible with Windows 7, 8 and 10, and the package includes the mouse.
Choose it when a cable is acceptable and you want direct USB use. It is less suitable for a laptop setup where you frequently move between locations.
The rubber coating gives the body a softer feel under the palm. Wiping it with a slightly damp cloth and letting it dry can keep that grip consistent over time.
At 1000 DPI, pointer movement stays controlled for office tasks and detailed selection. At 1600 DPI, you cover more screen distance with less hand movement, which many users prefer on larger displays.
Route the cable so it does not pull against the mouse during use. A stable cable position helps keep clicks and tracking consistent throughout the day.
Which wireless left handed mouse fits smaller hands?
SUNGI is the clearest small-to-medium-hand option among the simple vertical wireless mice, while MEETION adds rechargeable power and multiple wireless modes. KUNSI follows the same basic layout but is best for buyers who want a straightforward USB receiver.
Hand size is the main dividing line here. A mouse aimed at smaller hands can feel easier to control, while a larger body may suit users who prefer more palm support.
Power and connection create the next split. Rechargeable models remove the need for spare batteries, while receiver-based models keep setup simple but tie up a USB port.
Check the side-button notes before you choose, especially if you use a Mac. Some models in this group do not support forward and backward buttons on Mac OS, even though the mouse itself connects.
SUNGI Left-Handed Mouse: Best for small to medium hands
- Left-handed vertical design
- 800/1200/1600 DPI
- Forward and backward buttons
- 2.4 GHz wireless receiver
SUNGI is shaped for small to medium left hands and adds forward and backward buttons for web browsing. Its 3-level DPI control and wireless USB receiver keep the layout simple for everyday laptop or PC use.
Pros
- Small to medium hand fit
- Three DPI levels
- Wireless receiver included
Cons
- Not Bluetooth
- Requires 2 AAA batteries
SUNGI is designed for small to medium-sized left hands and uses a vertical grip with a thumb rest. The forward and backward buttons help with web browsing, while 800, 1200 and 1600 DPI settings let you adjust pointer speed.
It connects through a 2.4 GHz USB receiver and is not Bluetooth. The mouse enters sleep mode after inactivity and wakes when you press a button.
Two AAA batteries are required and are not included. The package includes the wireless mouse and USB receiver, and the stated compatible platforms include Windows, Mac, Chrome and Linux.
SUNGI makes sense when hand size and basic browsing controls matter most. It is less appealing if you want rechargeable power or Bluetooth.
The rubber-oil surface is meant to feel comfortable in the palm. A gentle wipe now and then will keep it from picking up grime that can make the grip slippery.
Sleep mode helps save battery power, but note that the first click after inactivity may wake the mouse rather than register as a normal click. That small delay is worth knowing if you use the mouse in short bursts.
MEETION Left-Handed Wireless Ergonomic Vertical Mouse: Best for rechargeable multi-device use
- Bluetooth 5.0 and 3.0
- 2.4G wireless
- Rechargeable battery
- 1200/1600/2400/3200 DPI
MEETION combines a left-handed vertical body with Bluetooth, 2.4G wireless and a rechargeable battery. Four DPI settings and forward and backward buttons make it flexible for work across compatible Windows and Mac devices.
Pros
- Rechargeable design
- Bluetooth and 2.4G options
- Four DPI settings
Cons
- Not compatible with Android TV or older Linux systems
- Recommended hand length is specific
MEETION BTM010 is the most flexible wireless option for users who want Bluetooth, 2.4G wireless and rechargeable power in one left-handed vertical mouse. It has a recommended hand length of 6.7 to 7.1 in, so measure your hand before choosing it.
The 6-button design includes forward and backward controls. Four DPI settings run from 1200 to 3200, giving you more sensitivity steps than the 800 to 1600 DPI models in this roundup.
The package includes the mouse, USB-A receiver, Type-C charging cable and user manual. It supports Windows 10 and 11, macOS 10.15 and above, and some other platforms, but it is not compatible with Android TV or older Linux systems.
Choose MEETION when rechargeable power and connection choice outweigh a simpler office design.
The wider DPI range suits users who move between a laptop screen and a larger external monitor. Lower settings help with precise selection, while higher settings reduce hand travel when you scroll through long pages or timelines.
Rechargeable power removes the need to buy disposable batteries. Keep the Type-C cable with your charging setup so the mouse is ready when the battery runs low.
KUNSI Left Handed Mouse: Best for basic wireless ergonomics
- Left-handed vertical design
- 800/1200/1600 DPI
- Forward and backward buttons
- 10 m wireless range
KUNSI keeps the core layout simple: a left-handed vertical body, six buttons, three DPI levels and a USB receiver. It fits buyers who want side buttons for browsing without Bluetooth or rechargeable power.
Pros
- Three DPI settings
- 10 m stated range
- Simple USB wireless setup
Cons
- Forward and backward buttons are unavailable on Mac OS
- Requires 2 AAA batteries
KUNSI gives you the basic left-handed vertical layout with six buttons, three DPI settings and a 10 m stated wireless range. Its forward and backward controls suit web browsing on compatible Windows systems.
The 800, 1200 and 1600 DPI settings cover common office and laptop use. Connection is through a 2.4 GHz USB receiver, which sits in the bottom of the mouse.
Two AAA batteries are required and are not included. The forward and backward buttons are unavailable on Mac OS, so Mac users should choose another model here if those controls are essential.
KUNSI is a reasonable fit when you want a simple wireless vertical mouse and do not need Bluetooth or rechargeable power.
The simple layout suits a home office or study desk where you use one computer most of the time. Plug in the receiver, add batteries, and the mouse is ready without extra software.
Storing the receiver in the bottom of the mouse helps when you carry it between rooms. Check that space before moving the mouse so the receiver does not get lost.
Which left handed mouse has the most programmable buttons?
The Razer Naga has the most programmable controls by a wide margin, while ELECOM offers a more moderate six-button trackball layout. Logitech Lift sits between them for office users who want customizable shortcuts without a gaming-style thumb grid.
The right choice depends on how many commands you actually need at your thumb. Two browsing buttons suit the web, while a full grid suits games, editing timelines and frequent shortcuts.
Setup time rises with button count. Programmable models reward users who assign commands methodically and avoid filling every button at once.
Razer RZ01-01050100-R3M1 Naga Left-Handed: Best for MMO button control
- 12 programmable thumb buttons
- 17 total buttons
- 8200 DPI laser sensor
- USB connection
The left-handed Razer Naga is the specialist pick for users who need far more than two side buttons. Its 12-button thumb grid, 17 total buttons and 8200 DPI laser sensor suit MMO controls, macros and hotkeys.
Pros
- Large programmable thumb grid
- High maximum DPI
- Left-handed ergonomic shape
Cons
- More buttons require setup time
- Designed for PC and Windows
Razer Naga is the clear pick for MMO controls and large shortcut layouts. Its 12-button thumb grid gives you far more side controls than the other mice here, and the mouse has 17 buttons in total.
The 8200 DPI 4G laser sensor targets high-sensitivity use. Each button can be customized for skills, macros and hotkeys through Razer's configurator, according to the product information.
This is a wired USB mouse for PC and Windows. The package includes the Razer Speedflex cable, and the body uses a left-handed ergonomic design.
The trade-off is complexity. If you only need forward and backward browsing, a six-button vertical mouse will be easier to set up and use.
Build your layout around a small set of frequent actions first. Keep movement and core clicks separate from the thumb grid, then add macros only after the basic positions feel natural.
The high DPI ceiling suits fast turns and wide screen movement in games. Lowering sensitivity can help with precise aiming, so reserve the highest settings for less exact cursor work.
Cherry MW: Best for a switchable office mouse
- 45-degree ergonomic shape
- Two thumb buttons
- Three-level resolution
- Switchable left/right click function
Cherry MW 4500 uses a 45-degree shape and two thumb buttons for forward and backward browsing. Its switchable left/right click function also gives you a way to change the button arrangement without changing system settings.
Pros
- 45-degree ergonomic shape
- Switchable click function
- Three-level resolution
Cons
- Maximum resolution is 1200 DPI
- Compatible-device data names laptops
Cherry MW 4500 is a good office option when you want two thumb buttons and a switchable click layout. Its 45-degree ergonomic design keeps your hand from resting completely flat, while the resolution changes across 3 levels up to 1200 DPI.
The two thumb buttons move between previous and next pages. A button also switches the left and right click function without changing system settings.
This wireless USB mouse uses a small nano receiver that can remain in a laptop or sit in the mouse. Batteries are included, and the mouse is compatible with laptops.
Choose Cherry when click-layout flexibility matters more than a high DPI ceiling or extensive programmable controls.
The switchable click layout can help if you share a workstation or change handedness for a task. It avoids digging into system settings, which makes the change quick at the desk.
The 45-degree shape is a middle ground between a flat mouse and a full vertical design. It suits users who want a less flat wrist position without moving to a tall upright grip.
How to choose a left handed mouse with side buttons
Start with the side-button job. Forward and backward buttons are enough for browsing, but programmable buttons make more sense for repeated shortcuts, editing commands or game actions.
Do you need programmable buttons or browser buttons?
A left handed mouse with programmable buttons gives you more control than a basic side-button model, but it also adds setup work. ELECOM has 6 assignable buttons, Logitech Lift has customizable buttons, and Razer Naga offers a 12-button thumb grid.
For simple browsing, use the forward and backward buttons on SHARE SUNSHINE, SUNGI, Perixx, Cherry, MEETION or KUNSI. Confirm Mac support before buying because SHARE SUNSHINE and KUNSI specify that their forward and backward buttons are unavailable on Mac OS.
If a trackball sounds better than a sliding mouse, our guide to the best trackball mouse with programmable buttons covers another way to get remappable controls. For an upright grip with programmable controls, see the best vertical mouse with programmable buttons guide.
Start by listing the actions you repeat most. Browsing back and forth needs only two buttons, while copy, paste, save and undo may justify a programmable layout.
Hand size should come next in your decision. Check the stated fit for small to medium hands, large hands, or a specific hand length before you compare button counts.
Connection and power determine how the mouse fits your desk. Bluetooth suits multiple devices, a USB receiver suits a single computer, and a cable removes battery concerns entirely.
DPI is the final check, not the first. Most office work sits comfortably in a modest range, while gaming and detailed design may benefit from higher settings.
Should you choose vertical, standard or trackball control?
Vertical mice such as Logitech Lift, Perixx, SUNGI, MEETION and KUNSI keep the hand in a more upright grip. SHARE SUNSHINE also uses a vertical left-hand design, while Cherry uses a 45-degree shape.
The ELECOM uses a thumb-controlled trackball, which changes how you move the pointer. Razer Naga uses a left-handed ergonomic gaming shape with a large thumb-button grid.
Hand fit matters as much as the shape. Logitech Lift targets small to medium left hands, SUNGI targets small to medium hands, and MEETION recommends a hand length of 6.7 to 7.1 in.
Is wireless or wired better for side-button use?
Wireless is useful when you want a cleaner desk or move between devices. Logitech Lift supports Bluetooth and Logi Bolt, MEETION supports Bluetooth and 2.4G, and the other wireless picks here use USB receivers.
A wired mouse avoids battery changes and receiver management. Perixx and Razer use USB connections, so they suit a fixed desk where cable movement is not a concern.
For a quiet wireless mouse with browsing controls, compare this roundup with the best silent mouse with side buttons.
How should you set up side buttons?
Place the mouse so your forearm can rest without forcing your wrist into a sharp angle. Start with the middle DPI setting, then move lower for precise pointer work or higher when you need less hand movement across the desk.
Assign only the shortcuts you use often. For programmable models, keep a simple layout first, then add commands after you know which buttons are easy to reach without changing your grip.
Clean the sensor area and the trackball opening with care, and keep the USB receiver accessible if your mouse uses one. Replace or recharge the power source when pointer movement becomes inconsistent.
Final verdict on the best left handed mouse with side buttons
The Logitech Lift is the best all-around left handed mouse with side buttons for small to medium left hands, quiet office work and customizable controls. Pick SHARE SUNSHINE for adjustable DPI and a simple vertical wireless layout, or Razer Naga for MMO shortcuts and a 12-button thumb grid.
Choose ELECOM if you prefer thumb-controlled trackball movement, Perixx if you want a wired desk mouse, and MEETION if rechargeable power and Bluetooth matter most. For basic browsing, SUNGI, Cherry and KUNSI cover the essential side-button use with different trade-offs in power, click layout and Mac support.
Our score weighs stated specs, features and buyer feedback against what you're shopping for: accessible left-hand side controls and useful remapping options.
If your work is mostly documents and web browsing, prioritize quiet clicks, hand fit and a connection that matches your devices. That points toward Lift for a polished office setup.
If you play MMOs or use many shortcuts, the extra buttons on Razer Naga earn their setup time. You will get the most value when you assign commands you use every session.
For a trackball desk, ELECOM changes how you move the cursor and keeps the mouse body still. That trade-off suits users who want precision from the thumb rather than sliding the whole mouse.
Our top 3 picks at a glance
-
1
Best for adjustable DPI on a budget
SHARE SUNSHINE Wireless Mouse Ergonomic Vertical Left-Handed Mouse
9.7/10 our score
See it on Amazon -
2
Best for quiet everyday work
Logitech Left Handed Lift Vertical Ergonomic Wireless
9.7/10 our score
See it on Amazon -
3
Frequently asked questions
What is the best left handed mouse with side buttons?
The Logitech Lift is the best left handed mouse with side buttons for most office users because it combines a left-hand vertical shape, customizable buttons, quiet clicks and Bluetooth or Logi Bolt connectivity.
Choose SHARE SUNSHINE for three DPI levels, or Razer Naga for a large programmable thumb-button grid.
Are side buttons useful on a left-handed mouse?
Yes. Forward and backward side buttons can speed up web browsing and document movement, while programmable buttons can hold shortcuts or game commands.
Check the operating system notes before buying.
SHARE SUNSHINE and KUNSI do not recognize their forward and backward buttons on Mac OS, while ELECOM supports button assignment through its software.
What should I check before buying a left handed mouse with programmable buttons?
Check the hand orientation, button count, software support and connection type first. ELECOM has 6 programmable buttons through Mouse Assistant, while Razer Naga has 12 programmable thumb buttons and 17 total buttons.
Also check hand fit, DPI settings and whether you prefer a cable, USB receiver, Bluetooth or rechargeable power.
Are vertical left-handed mice better for wrist comfort?
A vertical shape places your hand in a more upright position, which some users may find more natural than a flat mouse. Logitech Lift uses a 57-degree shape, while Cherry MW uses a 45-degree design.
Comfort depends on hand size, grip and adjustment time, so compare the stated dimensions and recommended hand fit.
